Community Mobilization and HIV/STI Epidemiology of Female Sex Workers in Mexico

墨西哥女性性工作者的社区动员和艾滋病毒/性传播感染流行病学

• 批准号: 9341639
• 负责人: Lianne A Urada
• 金额: $ 15.42万
• 依托单位: SAN DIEGO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9341639
• 关键词: AIDS prevention; Address; Advocacy; Advocate; Affect; Alcohol consumption; Alcohol dependence; Alcohol or Other Drugs use; Applications Grants; Attention; Behavior; Behavioral; Biological; Border Crossings; California; Caribbean region; Cities; Coercion; Communities; Conscious; Cost-Benefit Analysis; Data; Data Analyses; Data Collection; Dependence; Development Plans; Diffuse; Drug usage; Ensure; Epidemiology; Ethics; Evaluation Methodology; Event; Face; Focus Groups; Forcible intercourse; Funding; Future; General Population; Goals; Guidelines; HIV; HIV Infections; HIV risk; HIV/STD; Harm Reduction; Health; Health Services Accessibility; Human Rights; India; Individual; Infection; International; Intervention; Intervention Studies; Interview; Knowledge; Lead; Learning; Literature; Marijuana; Measurement; Measures; Mentored Research Scientist Development Award; Mentors; Methods; Mexico; Modeling; National Institute of Drug Abuse; Nature; Needles; Outcome; Pharmaceutical Preparations; Police; Population; Positioning Attribute; Prevalence; Prevention; Preventive Intervention; Public Health; Publishing; Readability; Recording of previous events; Reporting; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Rights; Risk; Risk Behaviors; Role; Shares syringes; Surveys; Syringes; Testing; Time; Training; United States; Universities; Unsafe Sex; Violence; Vulnerable Populations; Woman; Work; World Health Organization; base; career; career development; clinical biomarkers; cognitive testing; design; empowerment; experience; female sex worker; follow-up; high risk; illicit drug use; improved; injection drug use; interest; parent grant; peer; programs; sex; sex risk; skills; social; solidarity; substance abuse epidemiology; transmission process; violence victimization

DESCRIPTION (provided by applicant): This Mentored Research Scientist Development Award (K01) will enable me to 1) acquire expertise in the research methods of developing structural HIV prevention interventions targeting substance using female sex workers (FSWs); 2) increase knowledge of substance abuse epidemiology, assessment and prevention; 3) obtain additional training in the culturally competent ethical conduct of research involving behavioral and biological HIV/STI data collection, violence measurement, and structural interventions in a new international setting; 4) learn how to design RCTs of interventions and conduct related longitudinal data analyses (GLMM); 5) hone skills needed for a successful academic career studying the intersection of substance use, HIV/STI acquisition, and structural risk and protective factors among high risk populations, including grantsmanship and disseminating scientific research findings nationally and internationally. My career development plan will include a mixture of didactic courses, seminars, hands-on field research experience, and mentored independent studies which will provide me with training in intervention evaluation methodologies, substance use epidemiology, and clinical biomarkers. For example, I will take courses in longitudinal data analyses (e.g. event history and survival, and cost-benefit analyses). I will work with a world-renowned mentoring team and an infrastructure already in place in Mexico, with the goal of applying what I learn to other national contexts as well. I will train in intervention adaptation while simultaneously practicing rigorous RCT evaluation methodologies (Generalized Linear Mixed Modeling (GLMM)) on existing data, with the goal of becoming one of a few structural HIV prevention intervention researchers for FSWs worldwide. My proposed K01 project "Mujeres Unidas" (Women United) will be embedded in the NIDA funded parent grant, "Proyecto Mapa de Salud" (R01DA028692-01, PI: Brouwer), which explores HIV/STI transmission among FSWs and other vulnerable populations along the Mexico/U.S. border. In Tijuana, Mexico, Mujeres Unidas will 1) qualitatively interview FSWs (N=30) and FSW advocates/organizers (N=20) about community mobilization and the role of substance use; 2) adapt measures of community mobilization to the Tijuana context through cognitive testing with FSWs (n=10) to ensure readability and acceptability, and 3) determine the prevalence of community mobilization participation and its association with substance use, HIV/STI prevalence and sexual risk behaviors among FSWs by adding adapted measures to the parent grant's 12- month follow up surveys (N=300 FSWs). Results will generate pilot data for a future R34 grant application to pilot/feasibility test an adapted preventive intervention targeting drug use and HIV infection acquisition.

描述（由申请人提供）：获得指导研究科学家发展奖 (K01) 将使我能够 1) 获得针对使用女性性工作者 (FSW) 的物质开发结构性艾滋病毒预防干预措施的研究方法方面的专业知识； 2) 增加药物滥用流行病学、评估和预防方面的知识； 3) 获得在文化上合格的伦理研究行为方面的额外培训，涉及新的国际环境中的行为和生物学艾滋病毒/性传播感染数据收集、暴力测量和结构干预； 4）学习如何设计干预措施的随机对照试验并进行相关的纵向数据分析（GLMM）； 5) 磨练成功学术生涯所需的技能，研究高危人群中物​​质使用、艾滋病毒/性传播感染、结构性风险和保护因素的交叉点，包括资助和在国内和国际上传播科学研究成果。我的职业发展计划将包括教学课程、研讨会、实践现场研究经验和指导独立研究，这些将为我提供干预评估方法、物质使用流行病学和临床生物标志物方面的培训。例如，我将学习纵向数据分析课程（例如事件历史和生存以及成本效益分析）。我将与世界知名的指导团队和墨西哥已有的基础设施合作，目标是将我学到的知识应用到其他国家。我将接受干预适应培训，同时根据现有数据实践严格的 RCT 评估方法（广义线性混合模型 (GLMM)），目标是成为全球少数几个针对 FSW 的结构性 HIV 预防干预研究人员之一。我提议的 K01 项目“Mujeres Unidas”（妇女联合）将嵌入 NIDA 资助的家长赠款“Proyecto Mapa de Salud”（R01DA028692-01，PI：Brouwer）中，该项目探讨墨西哥/美国沿线的 FSW 和其他弱势群体中的 HIV/STI 传播。边界。在墨西哥蒂华纳，Mujeres Unidas 将 1) 定性采访 FSW（N=30）和 FSW 倡导者/组织者（N=20），了解社区动员和物质使用的作用； 2) 通过对 FSW (n=10) 进行认知测试，使社区动员措施适应蒂华纳的情况，以确保可读性和可接受性，以及 3) 通过在家长补助金的 12 个月随访调查（N=300 FSW）中添加适应措施，确定社区动员参与的普遍程度及其与 FSW 中物质使用、艾滋病毒/性传播感染流行率和性危险行为的关系。结果将为未来 R34 拨款申请生成试点数据，以试点/可行性测试经过调整的预防性干预目标 吸毒和艾滋病毒感染。