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中文摘要
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摘要/摘要(试点项目计划) 试点项目计划(PPP)通过支持试点项目,为M-LEEaD中心的使命做出贡献 鼓励创新,创造力和多学科合作,特别是在基础科学家之间, 临床研究人员、社区和监管利益相关者。试点项目是一个重要的 吸引新的个人到我们中心的机制,并提供支持,以生成初步数据, 争取外部资金。试点项目计划的目的是:1)吸引知名调查人员 新来我们中心的人可以提供新的见解和方法来解决有关关系的问题 (2)鼓励创新、创造力, 多学科合作,特别是基础科学家,临床研究人员和社区之间的合作, 监管利益相关者; 3)促进我们的中心成员快速有效地响应新的和 快速周转的研究机会,特别是来自NIEHS的机会; 4)为以下方面提供重要支持 早期研究人员为开发独立研究项目提供初步数据, 争取独立融资。这一方法在我们最初的融资期间取得了成功, 支持的初级教师的数量,形成的新合作,科学家的参与 作为试点项目的结果,参与中心活动的环境健康研究新手 计划,提交的外部资助申请数量,最终出版物数量和职业生涯 进展情况,所有这些都在进度报告中概述。试点项目管理方面的重要进展 上一个周期的项目计划包括与其他P30中心组成评审联盟, 有助于提高审查的客观性,并避免审查可能导致的利益冲突, 其他人在同一个机构。在下一个周期的试点项目计划将建立在势头 通过继续广泛分发《申请书》, 公共卫生学院和医学院,继续审查财团和继续 核心设施。我们还将继续在审查委员会中包括一名COEC成员的做法 负责对建议书进行排序,以确保他们的投入。这些做法将继续 在试点项目计划的第一个周期开始了开创性的工作。
英文摘要
Summary/Abstract (Pilot Project Program) The Pilot Project Program (PPP) contributes to the mission of the M-LEEaD Center by supporting pilot projects that encourage innovation, creativity, and multidisciplinary collaborations, especially among basic scientists, clinical researchers, and community and regulatory stakeholders. The Pilot Project Program is an important mechanism for attracting new individuals to our center and for providing support to generate preliminary data to compete for external funding. The aims of the Pilot Project Program are to: 1) attract established investigators new to our center who can provide new insights and approaches to questions regarding the relationships between lifestage environmental exposures and disease; 2) encourage innovation, creativity, and multidisciplinary collaborations, especially between basic scientists, clinical researchers, and community and regulatory stakeholders; 3) facilitate our center members’ ability to respond quickly and effectively to new and quick-turnaround research opportunities, especially those from NIEHS; and 4) provide important support for early-stage investigators to generate preliminary data for developing independent research projects and compete for independent funding. This approach was successful in our initial funding period as evidenced by the number of junior faculty supported, the new collaborations that were formed, the participation of scientists new to environmental health research that participated the center activities as a result of the Pilot Project Program, the number of external grant applications submitted, the number of resulting publications, and career advancement, all as summarized in the progress report. Important advances in the administration of the Pilot Project Program during the last cycle include the formation of a reviewer consortium with other P30 centers to help improve objectivity of the reviews as well as avoid conflicts of interest that can result from reviews by others in the same institution. In the next cycle of the Pilot Project Program will build on the momentum generated in the first four years by continuing the wide distribution of the Request for Applications throughout the School of Public Health and the Medicial School, continuing the Reviewer consortium and continuing the Core facilities. We will also continue our practice of including a COEC member on the review committee responsible for ranking of the proposals to assure their input. Together, these practices will continue the groundbreaking work started in the first cycle of the Pilot Project Program.
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Epigenomics of Systemic Autoimmunity
Does Demethylation of the Inactive X Contribute to Lupus in Women?
  • 批准号:
    8245569
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    2011
  • 负责人:
    BRUCE C. RICHARDSON
  • 依托单位:
Does Demethylation of the Inactive X Contribute to Lupus in Women?
  • 批准号:
    8398943
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    2011
  • 负责人:
    BRUCE C. RICHARDSON
  • 依托单位:
Does Demethylation of the Inactive X Contribute to Lupus in Women?
  • 批准号:
    8597403
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    2011
  • 负责人:
    BRUCE C. RICHARDSON
  • 依托单位:
海外基金