Personalisation of Aspirin Adjuvant Therapy in Patients with Colorectal Cancer
Personalisation of Aspirin Adjuvant Therapy in Patients with Colorectal Cancer
批准号:
nhmrc : GNT1138047
负责人:
A/Pr Oliver Sieber
金额:
$76.26万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
Aspirin use is associated with a reduced risk of bowel cancer recurrence. However, benefit appears limited to a subset of patients, and some individuals experience side effects. We will analyse tumour samples from patients participating in the ASCOLT clinical trial of aspirin to identify molecular features that can predict who will benefit from aspirin. Predictive biomarkers would be of substantial clinical utility for guiding treatment, minimising toxicity and improving disease outcomes.
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Translational genomics and combinatorial drug discovery to improve outcomes for patients with colorectal cancer
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批准号:nhmrc : 1136119
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项目类别:Research Fellowships
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资助金额:$43.29万
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财政年份:2018
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负责人:A/Pr Oliver Sieber
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依托单位:
Translational genomics and combinatorial drug discovery to improve outcomes for patients with colorectal cancer
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批准号:nhmrc : GNT1136119
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项目类别:Research Fellowships
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资助金额:$64.02万
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财政年份:2018
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负责人:A/Pr Oliver Sieber
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依托单位:
Personalisation of Aspirin Adjuvant Therapy in Patients with Colorectal Cancer
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批准号:nhmrc : 1138047
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项目类别:Project Grants
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资助金额:$51.56万
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财政年份:2018
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负责人:A/Pr Oliver Sieber
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依托单位:
Role of the EHF transcription factor in regulating the differentiation status of colon cancers
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批准号:nhmrc : GNT1107831
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项目类别:Project Grants
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资助金额:$62.2万
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财政年份:2016
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负责人:A/Pr Oliver Sieber
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依托单位:
Role of the EHF transcription factor in regulating the differentiation status of colon cancers
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批准号:nhmrc : 1107831
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项目类别:Project Grants
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资助金额:$42.63万
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财政年份:2016
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负责人:A/Pr Oliver Sieber
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依托单位:
Population genetics and functional genomics approaches to improve outcomes for patients with colorectal cancer
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批准号:nhmrc : 1062226
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项目类别:Career Development Fellowships
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资助金额:$31.11万
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财政年份:2014
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负责人:A/Pr Oliver Sieber
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依托单位:
Overcoming resistance to anti-EGFR antibody therapy in colorectal cancer using novel targeted PI3K and MEK inhibitors
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批准号:nhmrc : 1050177
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项目类别:Project Grants
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资助金额:$31.11万
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财政年份:2013
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负责人:A/Pr Oliver Sieber
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依托单位:
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