Phenotypic, genomic and informatic characterization of host-microbiota interactions to develop disease therapies

宿主-微生物群相互作用的表型、基因组和信息学特征，以开发疾病疗法

• 批准号: nhmrc : GNT1159239
• 负责人: Dr Samuel Forster
• 金额: $ 43.7万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/phenotypic-genomic-informatic-disease-therapies/1349285
• 关键词: Phenotypic; genomic; informatic; characterization; host

We now know that the bacteria found throughout our bodies play important, though poorly understood, roles in both disease and maintenance of health. In the human gut, we have identified novel bacteria, present in healthy individuals, that can drive inflammation in certain circumstances. As an emerging leader in microbiome, bioinformatics and innate immunity. I will identify novel therapeutic interventions to target these bacteria and block the inflammation for the treatment of diseases.

我们现在知道，在我们体内发现的细菌在疾病和维持健康方面都起着重要的作用，尽管人们对此知之甚少。在人类肠道中，我们已经发现了存在于健康个体中的新型细菌，它们可以在某些情况下驱动炎症。作为微生物组，生物信息学和先天免疫的新兴领导者。我将确定新的治疗干预措施，以针对这些细菌和阻止炎症治疗疾病。