Plasma lipidomic signatures for risk prediction and prevention of gestational diabetes

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Over 20,000 Australian women develop gestational diabetes (GDM) annually, increasing their risk of pregnancy complications, as well as diabetes and heart disease later in life. Lipids are a key source of energy for cells and often change during pregnancy, yet their role in GDM is unknown. Using novel techniques, I will measure hundreds of lipids to examine whether certain lipid species contribute to GDM development and whether these lipids are altered by diet, lifestyle, and/or drug therapies.