Plasmapheresis as a Novel treatment of Postural Tachycardia Syndrome: a randomised controlled trial

血浆置换术作为体位性心动过速综合征的新型治疗方法：一项随机对照试验

• 批准号: nhmrc : 1134261
• 金额: $ 6.62万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/plasmapheresis-novel-treatment-controlled-trial/948961
• 关键词: Plasmapheresis; Novel; treatment; Postural; Tachycardia

We aim to conduct a randomized controlled trial to test our hypothesis that the removal of autoantibodies (through plasmapheresis) will reduce the severity of symptoms in patients with postural tachycardia syndrome. We will be measuring symptom scores, cardiovascular fitness on exercise testing, heart rate and blood pressure responses during valsalva and orthostatic stress as well as the metabolic profiles and presence of autoantibodies in the blood of patients participating in the trial.

我们的目的是进行一项随机对照试验，以验证我们的假设，即去除自身抗体（通过血浆置换）将减少体位性心动过速综合征患者症状的严重程度。我们将测量症状评分、运动测试的心血管健康、瓦尔萨尔瓦和直立性应激期间的心率和血压反应以及参与试验的患者的代谢特征和血液中自身抗体的存在。