Potent broadly reactive neutralising HIV-1 monoclonal antibodies

成功的疫苗可以预防感染。对于艾滋病毒感染，迄今为止所有候选疫苗都失败了。在许多HIV-1感染者中，有很小比例的人不会发展为疾病。对于这些受感染的受试者，我们假设他们的免疫应答被更好地保存，因此他们将具有更强的抗体应答。我们已经准备好了我们的实验室，以培养这些强抗体，并利用它们来制造更好的HIV-1疫苗。

A successful vaccine prevents infection. For HIV infection all candidate vaccines thus far have failed. From the many HIV-1 infected individuals there are a very small percentage that do not progress to disease. For these infected subjects we hypothesise that their immune responses are much better preserved and hence they will have stronger antibody responses. We have geared up our laboratory to characterise these strong antibodies and use them in making a better HIV-1 vaccine.