Bronchiectasis and infection with the Human T-lymphotropic Virus 1 among Indigenous Australians

澳大利亚原住民中的支气管扩张和人类 T 淋巴细胞病毒 1 感染

• 批准号: nhmrc : 1012945
• 负责人: A/Pr Dale Mcphee
• 金额: $ 56.66万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/bronchiectasis-infection-human-indigenous-australians/109691
• 关键词: Bronchiectasis; infection; Human; lymphotropic; Virus

The Indigenous people of Central Australia have the highest reported prevalence of bronchiectasis in the world. In a recent study, we found infection with Human T -cell Lymphotropic Virus type 1 (HTLV-1) may contribute to the devlopment of bronchiectasis. The present study seeks to confirm this association and to determine whether increased HTLV-1 activity is associated with greater risk. This will require the development of assays that will improve diagnosis and assist in determining prognosis of HTLV infection.

据报道，澳大利亚中部的土著居民是世界上支气管扩张率最高的地区。在最近的一项研究中，我们发现感染人类T细胞嗜淋巴病毒1型（HTLV-1）可能有助于支气管扩张的发展。本研究旨在证实这种关联，并确定HTLV-1活性的增加是否与更高的风险相关。这就需要开发能够改善HTLV感染诊断和帮助确定预后的检测方法。