Smart polymer-DNA hybrids as recognition sites for advanced DNA nanotechnology applications.

该项目旨在设计和合成一个新的DNA共轭链转移剂家族，用于在广泛的2D和3D“智能”聚合物-DNA杂化材料中控制DNA的位置。这些生物共轭材料将被调查，以了解基本的自组装过程，支持新兴的动态DNA纳米技术。这项及时的研究将彻底改变生物启发的智能超材料在医疗诊断、DNA计算和DNA纳米机器中的应用。

This project aims to design and synthesise a new family of DNA-conjugated chain transfer agents for the positional control of DNA in a broad range of 2D and 3D 'smart' polymer-DNA hybrid materials. These bioconjugated materials will be investigated to understand the fundamental self-assembly processes which underpin emerging dynamic DNA nanotechnologies. This timely research will revolutionise the use of biologically inspired intelligent metamaterials for use in medical diagnostics, DNA computing and DNA nanomachines.