Precision treatment for multiple sclerosis: Maximising the effect of immunomodulatory therapy

多发性硬化症的精准治疗：最大化免疫调节治疗的效果

• 批准号: nhmrc : 1129189
• 负责人: Prof Helmut Butzkueven
• 金额: $ 36.8万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/precision-treatment-multiple-immunomodulatory-therapy/948361
• 关键词: Precision; treatment; multiple; sclerosis; Maximising

Response to therapy varies greatly among patients with multiple sclerosis (MS). The current lack of individualised MS therapy may lead to suboptimal MS management and accumulation of preventable disability. We will use MSBase, a large international MS cohort, to evaluate the effect of different treatment strategies and of highly effective and novel therapies. Identifying the patients who will benefit from these therapies, we will provide the key evidence for individualised MS management.

多发性硬化症(MS)患者对治疗的反应差异很大。目前缺乏个体化的多发性硬化症治疗可能导致次优的多发性硬化症管理和可预防的残疾的积累。我们将使用MSBase，一个大型的国际多发性硬化症队列，来评估不同治疗策略和高效新疗法的效果。确定哪些患者将从这些治疗中受益，我们将为个体化的多发性硬化症管理提供关键证据。