Cognitive neuroscience of spatial asymmetry: behaviour, genes and brain imaging

空间不对称的认知神经科学：行为、基因和大脑成像

• 批准号: FT130101488
• 负责人: Prof Mark Bellgrove
• 金额: $ 67.61万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT130101488
• 关键词: Cognitive; neuroscience; spatial; asymmetry; behaviour

When humans distribute their attention in space, biases or asymmetries of spatial attention exist. Healthy individuals exhibit a processing advantage favouring left space but this advantage is lost in disorders such as unilateral spatial neglect, ADHD and dyslexia. This project will develop novel electrophysiological methods to dissociate the sensory, attentional, decision-making and motoric contributions to spatial asymmetries. By interfacing electrophysiology with genetic, neurochemical and brain imaging methods, this project will comprehensively map the biology of spatial asymmetry. This knowledge is vital to developing effective treatments for disorders where atypical patterns of spatial asymmetry index neurological vulnerability.

人类在空间中分配注意力时，存在空间注意力的偏差或不对称。健康个体表现出有利于左侧空间的加工优势，但这种优势在单侧空间忽视、ADHD和阅读障碍等疾病中丧失。该项目将开发新的电生理方法来分离空间不对称的感觉，注意力，决策和运动的贡献。 通过将电生理学与遗传、神经化学和大脑成像方法相结合，该项目将全面绘制空间不对称的生物学图谱。 这方面的知识是至关重要的，开发有效的治疗疾病的非典型模式的空间不对称指数神经脆弱性。