Preclinical Studies in Xenotransplantation

异种移植的临床前研究

• 批准号: nhmrc : 558408
• 负责人: A/Pr Mark Nottle
• 金额: $ 81.98万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/preclinical-studies-xenotransplantation/82032
• 关键词: Preclinical; Studies; Xenotransplantation

Many people with organ failure need a transplant to survive. Unfortunately most patients who would benefit from a transplant are unable to receive one because of the shortage of living or deceased donors. A possible solution to this shortage is to use animal organs. Pigs are the most suitable animal donor. This project aims to produce and test genetically modified pigs which can provide organs that will be resistant to rejection when transplanted into human recipients.

许多器官衰竭的人需要移植才能生存。不幸的是，大多数可以从移植手术中受益的病人都无法接受移植手术，因为活着的或死去的捐赠者短缺。一个可能的解决办法是使用动物器官。猪是最合适的动物供体。该项目旨在生产和测试转基因猪，这些猪在移植到人体受体时可以提供抵抗排斥反应的器官。