Predictors of cardiovascular disease mortality in the Melbourne Collaborative Cohort Study
墨尔本合作队列研究中心血管疾病死亡率的预测因子
基本信息
- 批准号:nhmrc : 124317
- 负责人:
- 金额:$ 23.37万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:NHMRC Project Grants
- 财政年份:2000
- 资助国家:澳大利亚
- 起止时间:2000-01-01 至 2002-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The Melbourne Collaborative Cohort Study was set up in the early 1990s to investigate prospectively the role of diet and other lifestyle factors in causing common chronic diseases including common cancers and cardiovascular disease. Between 1990 and 1994, 41,500 people, aged 40-69 were recruited into the MCCS. About 30% of the cohort are southern European migrants to Australia who were deliberately over-sampled to extend the range of dietary and lifestyle exposures. Migrants from southern Europe have an adverse risk factor profile in relation to obesity, body fat distribution, physical activity patterns, diabetes, smoking, blood pressure and cholesterol levels, yet their death rates from heart disease are 30-40% lower than the Australian average. A major objective of this study is to investigate the possibility that particular aspects of the diet and cuisine of migrants from southern Europe (olive oil as the major dietary fat, and high intakes of a variety of vegetables and fruit) protect against heart disease and stroke by providing high levels of a wide range of natural antioxidants. It represents the most comprehensive prospective study of diet and cardiovascular disease mortality ever conducted in Australia. A particularly powerful feature is the combination of detailed self-reported dietary intake, the very wide range of exposures to dietary factors implicated in CVD (as risk factors or protective agents), and the objective markers of dietary intake (biochemical markers of dietary intake patterns in blood collected at recruitment, body weight, body fat and body fat distribution). The data should provide a strong rationale for specific dietary recommendations as part of population-based strategies to reduce the incidence of premature mortality from heart disease and stroke in the Australian population.
墨尔本协作队列研究成立于20世纪90年代初,旨在前瞻性地调查饮食和其他生活方式因素在导致常见慢性疾病(包括常见癌症和心血管疾病)中的作用。1990年至1994年期间,41,500名年龄在40-69岁之间的人被招募到MCCS。大约30%的队列是南欧移民到澳大利亚,他们被故意过度采样,以扩大饮食和生活方式暴露的范围。来自南欧的移民在肥胖、身体脂肪分布、身体活动模式、糖尿病、吸烟、血压和胆固醇水平方面具有不利的风险因素,但他们的心脏病死亡率比澳大利亚平均水平低30-40%。这项研究的一个主要目的是调查来自南欧的移民的饮食和烹饪的特定方面(橄榄油作为主要的膳食脂肪,以及各种蔬菜和水果的高摄入量)通过提供高水平的各种天然抗氧化剂来预防心脏病和中风的可能性。它代表了澳大利亚有史以来对饮食和心血管疾病死亡率进行的最全面的前瞻性研究。一个特别强大的功能是结合详细的自我报告的饮食摄入量,非常广泛的暴露于涉及CVD的饮食因素(作为风险因素或保护剂),以及饮食摄入的客观标志物(招募时收集的血液中饮食摄入模式的生化标志物,体重,体脂和体脂分布)。这些数据应该为特定的饮食建议提供强有力的理由,作为基于人口的战略的一部分,以减少澳大利亚人口中心脏病和中风的过早死亡率。
项目成果
期刊论文数量(0)
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会议论文数量(0)
专利数量(0)
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Prof Kerin O'Dea其他文献
Prof Kerin O'Dea的其他文献
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{{ truncateString('Prof Kerin O'Dea', 18)}}的其他基金
Community and individual resilience for positive health in Indigenous populations at risk for diabetes and cardiovascula
社区和个人对面临糖尿病和心血管疾病风险的原住民积极健康的恢复力
- 批准号:
nhmrc : 361617 - 财政年份:2005
- 资助金额:
$ 23.37万 - 项目类别:
NHMRC Strategic Awards
Community-Based Interventions to Reduce the Risk of Diabetes and Cardiovascular Disease in Indigenous Australians
以社区为基础的干预措施,降低澳大利亚原住民患糖尿病和心血管疾病的风险
- 批准号:
nhmrc : 124319 - 财政年份:2001
- 资助金额:
$ 23.37万 - 项目类别:
NHMRC Project Grants
Nutritional indicators and cardiovascular risk in aborigines and torres strait islanders
原住民和托雷斯海峡岛民的营养指标和心血管风险
- 批准号:
nhmrc : 981010 - 财政年份:1998
- 资助金额:
$ 23.37万 - 项目类别:
NHMRC Project Grants
Diabetes: is it a heart disease risk factor for Greek m igrants?
糖尿病:它是希腊移民患心脏病的危险因素吗?
- 批准号:
nhmrc : 974098 - 财政年份:1997
- 资助金额:
$ 23.37万 - 项目类别:
NHMRC Project Grants
Hplc fluorescence detector and autosampler
HPLC 荧光检测器和自动进样器
- 批准号:
nhmrc : 971467 - 财政年份:1997
- 资助金额:
$ 23.37万 - 项目类别:
NHMRC Infrastructure Grants
Management and Prevention of Diabetes in Aborigines and Torres Strait Islanders - Working Group meeting
原住民和托雷斯海峡岛民糖尿病的管理和预防 - 工作组会议
- 批准号:
nhmrc : 961484 - 财政年份:1996
- 资助金额:
$ 23.37万 - 项目类别:
NHMRC Project Grants
Obesity diabetes and cardiovascular diseases in Aborigi nes and Torres Strait Islanders
原住民和托雷斯海峡岛民的肥胖、糖尿病和心血管疾病
- 批准号:
nhmrc : 954605 - 财政年份:1995
- 资助金额:
$ 23.37万 - 项目类别:
Program
Diet exercise and body fat distribution in diabetic wom en
糖尿病女性的饮食锻炼和身体脂肪分布
- 批准号:
nhmrc : 950921 - 财政年份:1995
- 资助金额:
$ 23.37万 - 项目类别:
NHMRC Project Grants
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