Preventing Blindness: Blocking TGF¤-induced EMT and Cataract Development

预防失明：阻断 TGF¤ 诱导的 EMT 和白内障发展

• 批准号: nhmrc : 1024799
• 负责人: Prof Frank Lovicu
• 金额: $ 22.93万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/preventing-blindness-blocking-cataract-development/110373
• 关键词: Preventing; Blindness; Blocking; TGF; induced

Cataract, the loss of transparency of the eye lens, is a major cause of blindness. We have identified molecules in the lens important for maintenance of its transparency and plan to characterise their effectiveness in preventing cataract formation.

白内障，即失去晶状体的透明度，是失明的主要原因。我们已经确定了晶状体中维持其透明度的重要分子，并计划描述它们在预防白内障形成方面的有效性。