Prognostic significance of circulating tumour biomarkers in patients treated with curative-intent radiotherapy for NSCLC

循环肿瘤生物标志物对接受根治性放疗的 NSCLC 患者的预后意义

• 批准号: nhmrc : GNT1104139
• 负责人: A/Pr Olga Martin
• 金额: $ 87.71万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prognostic-significance-circulating-radiotherapy-nsclc/1346331
• 关键词: Prognostic; significance; circulating; tumour; biomarkers

More than 50% of cancer patients in Australia receive radiotherapy but many later die from distant metastases. This study of circulating biomarkers (tumour cells and DNA in the bloodstream) builds on evidence from research at Peter Mac showing that some lung cancers might spread during treatment with radiotherapy that would otherwise be curative. This study will help identify cancer patients at high risk of secondary cancers and could allow us to modify treatments to prevent them.

澳大利亚超过50％的癌症患者接受了放疗，但后来许多人死于遥远的转移。这项对循环生物标志物（血液中的肿瘤细胞和DNA）的研究基于彼得MAC的研究证据，表明某些肺癌在放疗治疗期间可能会散布，否则这将是治愈性的。这项研究将有助于鉴定有继发性癌症风险高风险的癌症患者，并可以使我们改变治疗以防止治疗。