Prognostic significance of circulating tumour biomarkers in patients treated with curative-intent radiotherapy for NSCLC

循环肿瘤生物标志物对接受根治性放疗的 NSCLC 患者的预后意义

• 批准号: nhmrc : 1104139
• 负责人: A/Pr Olga Martin
• 金额: $ 60.56万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prognostic-significance-circulating-radiotherapy-nsclc/662723
• 关键词: Prognostic; significance; circulating; tumour; biomarkers

More than 50% of cancer patients in Australia receive radiotherapy but many later die from distant metastases. This study of circulating biomarkers (tumour cells and DNA in the bloodstream) builds on evidence from research at Peter Mac showing that some lung cancers might spread during treatment with radiotherapy that would otherwise be curative. This study will help identify cancer patients at high risk of secondary cancers and could allow us to modify treatments to prevent them.

在澳大利亚，超过50%的癌症患者接受放射治疗，但许多人后来死于远处转移。这项对循环生物标志物（血液中的肿瘤细胞和DNA）的研究建立在Peter Mac研究的证据基础上，该研究表明，一些肺癌可能会在放射治疗期间扩散，否则将是治愈性的。这项研究将有助于识别继发性癌症高风险的癌症患者，并使我们能够修改治疗方法以预防它们。