PSA testing: a population-based longitudinal study of decision making, psychological effects and patterns of care

PSA 测试：基于人群的决策、心理影响和护理模式的纵向研究

• 批准号: nhmrc : 337601
• 负责人: A/Pr David Smith
• 金额: $ 38.47万
• 依托单位: Cancer Council NSW
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/psa-testing-population-patterns-care/100021
• 关键词: PSA; testing; population; based; longitudinal

Prostate cancer is the most commonly diagnosed cancer in Australian men and the second most common cancer- related cause of death. Since being introduced into Australia in 1988 the Prostate Specific Antigen (PSA) blood test has been widely adopted as a method for detecting early-stage asymptomatic prostate cancer. However there is controversy about the potential benefits and harms of testing for prostate cancer. Little has been documented in Australia about the information men receive when considering a PSA test, what happens to men after having an abnormal PSA test and the consequences of PSA testing (including physical and psychological effects). The aim of this study is to interview a representative community sample of men aged 50 to 84 years and resident in NSW to describe: (1) the decision-making process regarding PSA testing; (2) the psychological consequences of men's PSA testing experiences; and (3) patterns of care for men who have had an abnormal PSA test. The main outcomes from this study will include substantial information on the experiences of men regarding patterns of PSA participation (frequency of, and reasons for, testing), the clinical management of men who have had an abnormal PSA test, the psychological effects of PSA testing (both positive and negative) and how decisions about testing are being made. This will provide important information to assist GPs, urologists and Australian men make decisions about PSA testing. It will highlight areas of need regarding the information required by men for informed decision-making and the support they require when undergoing PSA testing to ensure positive psychological outcomes.

前列腺癌是澳大利亚男性中最常见的癌症，也是第二大常见的癌症相关死亡原因。自1988年引入澳大利亚以来，前列腺特异性抗原（PSA）血液检测已被广泛采用作为检测早期无症状前列腺癌的方法。然而，关于前列腺癌检测的潜在益处和危害存在争议。在澳大利亚，关于男性在考虑进行PSA检测时得到的信息、PSA检测异常后男性会发生什么以及PSA检测的后果（包括生理和心理影响）的记录很少。本研究的目的是采访一个具有代表性的社区样本的男性年龄在50至84岁，并居住在新南威尔士州描述：(1)关于PSA检测的决策过程；(2)男性PSA检测经历的心理后果；(3)对PSA检测异常的男性的护理模式。这项研究的主要结果将包括关于男性参与PSA模式（检测频率和原因）的经验的大量信息，PSA检测异常男性的临床管理，PSA检测的心理影响（阳性和阴性）以及如何做出检测决定。这将为全科医生、泌尿科医生和澳大利亚男性做出PSA检测的决定提供重要信息。它将突出男性在知情决策方面所需的信息以及他们在接受PSA检测以确保积极心理结果时所需的支持方面的需求。