Allosteric modulation and biased signalling at the calcium-sensing receptor
Allosteric modulation and biased signalling at the calcium-sensing receptor
批准号:
nhmrc : 1026962
负责人:
Dr Katie Leach
金额:
$42.42万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31
中文摘要
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英文摘要
The calcium-sensing receptor is a major target for the treatment of endocrine and bone disorders. However, the development of drugs for this receptor is challenging due to limited understanding of potential sites of drug interaction and how individual drugs may differentially change signalling from the receptor. This project will address these critical knowledge gaps, which may allow for improved therapeutic outcomes.
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Bias and allostery at the calcium sensing receptor
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批准号:FT160100075
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项目类别:ARC Future Fellowships
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资助金额:$44.88万
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财政年份:2017
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负责人:Dr Katie Leach
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依托单位:
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财政年份:2017
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负责人:Dr Katie Leach
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依托单位:
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批准号:nhmrc : GNT1085143
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项目类别:Project Grants
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资助金额:$61.42万
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财政年份:2015
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负责人:Dr Katie Leach
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依托单位:
Engendering biased signalling at the human calcium sensing receptor (CaSR) to correct pathophysiology
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批准号:nhmrc : 1085143
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项目类别:Project Grants
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资助金额:$42.27万
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负责人:Dr Katie Leach
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依托单位:
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批准号:11901349
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资助金额:26.0万元
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批准年份:2019
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负责人:陶涛
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依托单位:
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批准号:60802033
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资助金额:16.0万元
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批准年份:2008
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负责人:刘凯明
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依托单位: