Quantitative proteomic analysis of faecal biomarkers for colon cancer

结肠癌粪便生物标志物的定量蛋白质组学分析

• 批准号: nhmrc : 603130
• 负责人: Prof Edouard Nice
• 金额: $ 37.5万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/quantitative-proteomic-analysis-colon-cancer/100666
• 关键词: Quantitative; proteomic; analysis; faecal; biomarkers

We have identified a number of potential biomarkers present in the stools of patients with colorectal cancer (CRC). We will use quantitative mass spectrometric techniques that we have developed to validate these biomarkers on a large number of faecal samples from patients with CRC and multiple control groups. We believe these studies will lead to a new panel of biomarkers which will improve the detection of early forms of colon cancer, thus reducing death from this disease.

我们已经确定了一些潜在的生物标志物存在于结直肠癌（CRC）患者的粪便中。我们将使用我们开发的定量质谱技术，在CRC患者和多个对照组的大量粪便样本中验证这些生物标志物。我们相信这些研究将导致一组新的生物标志物，这将改善结肠癌早期形式的检测，从而减少这种疾病的死亡。