Colorectal Cancer Membrane Protein Interactomics [A Major Discriminator of Clinical Outcome]

结直肠癌膜蛋白相互作用组学 [临床结果的主要判别因素]

• 批准号: nhmrc : 1010303
• 负责人: Prof Edouard Nice
• 金额: $ 42.93万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/colorectal-cancer-membrane-clinical-outcome/109477
• 关键词: Colorectal; Cancer; Membrane; Protein; Interactomics

This project studies the molecular causes of colorectal cancer (CRC) malignancy because CRC is the 2nd most common malignancy by incidence and cause of death in the Western world. It currently results in 13.1% of Australian cancer deaths. The aim of this NHMRC project is to gain a detailed understanding of how particular cell membrane proteins interact with each to give cancer cells the ability to invade and spread.

该项目研究结直肠癌（CRC）恶性肿瘤的分子原因，因为CRC是西方世界第二大常见的恶性肿瘤，发病率和死亡原因。目前，它导致了澳大利亚13.1%的癌症死亡。这个NHMRC项目的目的是详细了解特定的细胞膜蛋白如何相互作用，使癌细胞能够入侵和扩散。