Randomised, double-blind, placebo controlled trial of lithium carbonate for the management of human cannabis withdrawal

碳酸锂用于管理人类大麻戒断的随机、双盲、安慰剂对照试验

• 批准号: nhmrc : 556301
• 负责人: Dr Adam Winstock
• 金额: $ 34.91万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/randomised-double-blind-cannabis-withdrawal/76846
• 关键词: Randomised; double; blind; placebo; controlled

This project aims to help dependent cannabis users stop using cannabis by exploring the safety and effectiveness of lithium in reducing the severity of withdrawal that occurs on cessation of use. Participants will be admitted to an inpatient drug treatment unit (Sydney or Lismore) for 7 days and will be randomly assigned to receive either lithium or placebo. Participants receiving lithium are expected to have less severe withdrawal and higher rates of abstinence from cannabis at follow-up.

该项目旨在通过探索锂在减轻停止使用时发生的戒断严重程度方面的安全性和有效性，帮助依赖大麻的使用者停止使用大麻。参与者将被送往住院药物治疗病房（悉尼或利斯莫尔）治疗 7 天，并被随机分配接受锂剂或安慰剂治疗。预计接受锂治疗的参与者在随访中的戒断程度会减轻，大麻戒断率也会提高。