Reducing the greatest uncertainty in radiotherapy.

放射治疗中最薄弱的环节是确定治疗体积（轮廓）。临床试验轮廓勾画缺乏准确性和一致性已被证明会导致患者结局降低。轮廓的手动审查是资源密集型的，昂贵的，并且对于高级治疗无法及时实现。我们将使用4个临床试验数据集评估轮廓评估的自动化方法，改变未来研究的实践，并在临床中实现一致的评估。

The weakest link in radiotherapy is defining treatment volumes (contouring). Lack of accuracy and consistency in clinical trial contouring has been shown to result in reduced patient outcomes. Manual review of contouring is resource intensive, expensive and for advanced treatments unachievable in a timely fashion. We will assess an automated approach to contouring assessment using 4 clinical trial datasets, changing practice for future studies and enabling consistent assessment in the clinic.