An imaging-genomic approach to advance understanding of early cortical development and outcome after preterm birth

一种成像基因组方法，可促进对早产后早期皮质发育和结局的了解

• 批准号: nhmrc : 1194497
• 金额: $ 64.52万
• 依托单位国家: 澳大利亚
• 项目类别: Investigator Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://researchdata.edu.au/an-imaging-genomic-preterm-birth/1778826
• 关键词: imaging; genomic; approach; advance; understanding

In Australia, over 26,000 babies are born too early each year, with long-lasting consequences to their development. We do not know how preterm birth affects the newborn brain. In order to improve our understanding, I will combine neuroimaging and genetic data to uncover how preterm birth affects the development of the brain in newborns and how this imparts risk for poor cognitive and motor outcomes. This will allow us better plan and monitor clinical trials and treatments for these infants.

在澳大利亚，每年有超过 26,000 名婴儿过早出生，这对他们的发育造成了长期影响。我们不知道早产如何影响新生儿大脑。为了增进我们的理解，我将结合神经影像学和遗传数据来揭示早产如何影响新生儿大脑的发育，以及这如何带来认知和运动结果不良的风险。这将使我们能够更好地计划和监测这些婴儿的临床试验和治疗。