An integrated approach to identify the molecular mechanisms contributing to the pathogenesis of insulin resistance: targeting the liver and skeletal muscle

肌肉和肝脏无法利用血液中的糖是导致肥胖和糖尿病的一个主要问题。这些问题是如何发生的还不得而知。我的研究目标是找出肌肉和肝脏问题的原因，以及解决这些问题是否会减少肥胖和糖尿病。由于肥胖和糖尿病患者的数量预计将在未来十年翻一番，我们需要了解这些疾病的原因。

The inability of muscle and liver to utilise sugar from the blood is a major problem that contributes to the development of obesity and diabetes. How these problems occur is unknown. The goal of my research is to identify what causes the muscle and liver problem, and whether fixing these problems will reduce obesity and diabetes. Since the number of people with obesity and diabetes is predicted to double over the next decade, we need to understand the cause of these diseases.