An integrated systems biology approach for the development of new therapeutic strategies for the treatment of high grade glioma

一种综合系统生物学方法，用于开发治疗高级别神经胶质瘤的新治疗策略

• 批准号: nhmrc : 1028552
• 负责人: A/Pr Kerrie Mcdonald
• 金额: $ 46.44万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/an-integrated-systems-grade-glioma/110644
• 关键词: integrated; systems; biology; approach; development

Glioma, the most common adult brain cancer, is incurable. Recent advances now allow us to grow glioma cells directly from patients in the laboratory in a way that preserves the features of the original tumor. In this proposal we will systematically analyze such cells using state-of-the-art technologies to identify new processes important to glioma, which in turn should facilitate the identification of innovative therapeutic approaches.

神经胶质瘤是最常见的成人脑癌，无法治愈。最近的进展使我们能够在实验室中直接从患者身上培养神经胶质瘤细胞，并保留了原始肿瘤的特征。在这项提案中，我们将使用最先进的技术系统地分析这些细胞，以确定对胶质瘤重要的新过程，这反过来又有助于识别创新的治疗方法。