The biology and therapeutic manipulation of lymphatic vessels in human disease

人类疾病中淋巴管的生物学和治疗操作

• 批准号: nhmrc : 487900
• 负责人: Prof Marc Achen
• 金额: $ 379.33万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Programs
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/biology-therapeutic-manipulation-human-disease/77514
• 关键词: biology; therapeutic; manipulation; lymphatic; vessels

This proposal is for an established team of researchers and clinicians to explore the molecular control of the lymphatic system. This network of lymphatic vessels, located in organs throughout the body, is critical for regulation of tissue fluid and immune function. This program will explore the molecules which control the function of lymphatic vessels and their interactions with other cells in the body. It will greatly enhance our understanding of the lymphatic vessels and identify molecular targets for medicines designed to treat cancer, cardiovascular disease and lymphoedema.

这个提议是为了建立一个由研究人员和临床医生组成的团队来探索淋巴系统的分子控制。这种淋巴管网络位于全身器官中，对于调节组织液和免疫功能至关重要。该计划将探索控制淋巴管功能的分子及其与体内其他细胞的相互作用。它将极大地提高我们对淋巴管的理解，并为治疗癌症、心血管疾病和淋巴水肿的药物确定分子靶点。