The effect of adenotonsillectomy on neurocognitive functioning in children with upper airway obstruction

腺样体扁桃体切除术对上气道阻塞儿童神经认知功能的影响

• 批准号: nhmrc : 250369
• 负责人: A/Pr Peter Baghurst
• 金额: $ 12.39万
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/effect-adenotonsillectomy-neurocognitive-airway-obstruction/80784
• 关键词: effect; adenotonsillectomy; neurocognitive; functioning; children

Upper airway obstruction during sleep affects up to 3% of all children and is very frequently unrecognised. If severe it causes growth failure, developmental delay and heart failure. However, there is little information on the effects of less severe degrees of upper airway obstruction in children but recent work suggests that reduced academic performance may also be present in children with relatively mild degrees of upper airway obstruction. In particular, the areas most affected appear to be intelligence, memory, behaviour and attentional capacity . Currently it is unclear whether these deficits are due to sleep disruption or reduced nocturnal oxygen levels. The treatment of upper airway obstruction is the removal of adenoids and tonsils, however, it is unknown whether or not this improves the child's intellectual capacity. This study aims to be one of the first to critically evaluate the impact of upper airway obstruction during sleep on children's intelligence, memory, behaviour and attentional capacity, and the improvements wrought by the removal of the child's tonsils and adenoids.

睡眠中的上呼吸道阻塞影响了多达3%的儿童，并且经常无法识别。如果严重，它会导致生长障碍，发育迟缓和心力衰竭。然而，很少有关于上呼吸道阻塞程度较轻的儿童的影响的信息，但最近的研究表明，学业成绩下降也可能存在于上呼吸道阻塞程度相对较轻的儿童中。特别是，受影响最大的领域似乎是智力、记忆、行为和注意力。目前尚不清楚这些缺陷是由于睡眠中断还是夜间氧气水平降低。上呼吸道阻塞的治疗是切除腺样体和扁桃体，然而，这是否能改善儿童的智力尚不清楚。这项研究旨在成为第一个批判性评估睡眠期间上呼吸道阻塞对儿童智力，记忆力，行为和注意力的影响，以及切除儿童扁桃体和腺样体所带来的改善的研究之一。