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The effect of iron supplementation in pregnancy on child cognitive development

The effect of iron supplementation in pregnancy on child cognitive development
妊娠期补铁对儿童认知发展的影响
批准号:
nhmrc : 250431
负责人:
A/Pr Peter Baghurst
金额:
$6.11万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2003
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2003-01-01 至 2004-12-31

项目摘要

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中文摘要
翻译
在胎儿生命期间,大脑生长非常迅速,动物研究表明,母亲怀孕期间铁营养不足可能导致后代永久性的结构和发育问题。虽然这还没有在人类婴儿中进行过研究,但新的研究表明,母亲在怀孕期间的铁储备是婴儿在生命第一年期间铁储备的重要决定因素。铁营养影响后期发育的关键时期可能是在胎儿期(怀孕期间)。我们有机会通过评估早期妊娠期补铁研究中儿童的认知能力来测试胎儿期铁营养是否影响儿童发育。我们的目标是在4岁时对儿童进行评估,以确定怀孕期间的铁营养是否可以预测发育。这可能会改变我们给孕妇的饮食建议,以确保她们给婴儿最好的生命开始。
英文摘要
During fetal life the brain grows very rapidly and animal studies have shown that inadequate iron nutrition of mothers during pregnancy can result in permanent structural and developmental problems in the offspring. Although this has not been examined in human infants, new studies suggest that the iron stores of the mother in pregnancy are an important determinant of the baby's iron stores during the first year of life. It may be that the critical period where iron nutrition influences later development is in fetal life (during pregnancy). We have the opportunity to test whether iron nutrition in fetal life influences childhood development by assessing the cognitive abilities of children who were in our earlier study of iron supplementation in pregnancy. Our aim is to assess the children at 4 years to determine if iron nutrition in pregnancy predicts development. This may change the dietary advice we give pregnant women to ensure they give their babies the best start in life.
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