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The effect of Cytochrome P450 genotype on blood pressure and 20-HETE responses to lifestyle interventions

The effect of Cytochrome P450 genotype on blood pressure and 20-HETE responses to lifestyle interventions
细胞色素 P450 基因型对血压和 20-HETE 对生活方式干预反应的影响
批准号:
nhmrc : 634359
负责人:
Dr Natalie Ward
金额:
$49.59万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2013-12-31

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中文摘要
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英文摘要
The effectiveness of treatments to reduce heart disease risk can vary enormously between individuals. This is partly due to a persons genetic makeup. Fatty acid metabolites called cytochrome P450 metabolites of arachidonic acid (CYP450-AAM) can act on blood vessels and the kidney to regulate blood pressure. We will study the effect of having a variation in a gene that regulates CYP450-AAM on blood pressure and heart disease risk in combination with a high salt diet or weight reduction.
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Nitrate: studies of metabolism and effects on blood pressure
  • 批准号:
    nhmrc : 1066048
  • 项目类别:
    Project Grants
  • 资助金额:
    $27.09万
  • 财政年份:
    2014
  • 负责人:
    Dr Natalie Ward
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How dietary flavonoids improve vascular function
  • 批准号:
    nhmrc : 1049381
  • 项目类别:
    Project Grants
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  • 财政年份:
    2013
  • 负责人:
    Dr Natalie Ward
  • 依托单位:
Mechanisms of Endothelial Protection by Dietary Flavonoids
  • 批准号:
    nhmrc : 634387
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $34.56万
  • 财政年份:
    2010
  • 负责人:
    Dr Natalie Ward
  • 依托单位:
20-Hydroxyeicosatetraenoic acid and its effects on the endothelium.
  • 批准号:
    nhmrc : 404108
  • 项目类别:
    Early Career Fellowships
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    $21.87万
  • 财政年份:
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  • 负责人:
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  • 依托单位:
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