Mechanisms of Endothelial Protection by Dietary Flavonoids

膳食黄酮类化合物的内皮保护机制

• 批准号: nhmrc : 634387
• 负责人: Dr Natalie Ward
• 金额: $ 34.56万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanisms-endothelial-protection-dietary-flavonoids/96535
• 关键词: Mechanisms; Endothelial; Protection; Dietary; Flavonoids

This project will investigate the possibility that specifc compounds found in fruits and vegetables can help protect against cardiovascular disease. Some of these compounds (flavonoids) may directly affect blood vessels to improve their function. Some vegetable are very rich in nitrate and the interaction of flavonoids with nitrate may increase the production of nitric oxide, which improves blood vessel function and can lower blood pressure.

该项目将调查水果和蔬菜中发现的特定化合物是否有助于预防心血管疾病。其中一些化合物（类黄酮）可能直接影响血管，以改善其功能。一些蔬菜富含硝酸盐，类黄酮与硝酸盐的相互作用可能会增加一氧化氮的产生，从而改善血管功能，降低血压。