Characterising and exploiting hydrogen tunnelling in environmentally and medically important enzymes

表征和开发对环境和医学重要的酶中的氢隧道效应

• 批准号: DP130102144
• 负责人: Prof Michelle Coote
• 金额: $ 23.45万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-31 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP130102144
• 关键词: Characterising; exploiting; hydrogen; tunnelling; environmentally

Theory and experiment will be used to study environmentally and medically important enzymes, and quantify the role that hydrogen tunnelling plays in their activity. The project will determine the basis of their remarkable ability to catalyse chemical reactions, and to engineer and design more efficient proteins and pharmaceuticals.

理论和实验将用于研究环境和医学上重要的酶，并量化氢隧道在其活性中的作用。该项目将确定它们催化化学反应的非凡能力的基础，并设计和设计更有效的蛋白质和药物。