The FREEDOM Study: a RCT of sunlight and calcium to reduce vitamin D deficiency in older people in residential care

FREEDOM 研究：通过阳光和钙来减少寄宿护理老年人维生素 D 缺乏症的随机对照试验

• 批准号: nhmrc : 402639
• 负责人: Prof Ian Cameron
• 金额: $ 55.94万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/freedom-study-rct-residential-care/96604
• 关键词: FREEDOM; Study; RCT; sunlight; calcium

The proposed study emanates from a large ongoing epidemiological study on falls and fractures in the elderly (the FREE study). Falls and fractures are major problems in the elderly. This is the genesis for the FREEDOM (Falls Risk Epidemiology: Effect of vitamin D on skeletal Outcomes and other Measures) intervention study. The FREEDOM study will evaluate the effect of a public health strategy to reduce falls and fractures in older people living in residential care (namely appropriate sun light exposure and calcium supplementation) in a randomised trial. The primary endpoints of this study will be reduction in falls and change in vitamin D levels. Other endpoints will be change in motor function, mood, bone turnover and fracture incidence. The proposed public health strategy to be examined is readily transferable to routine practice and would have very good feasibility for easy implementation and are generally applicable to the residential care setting, where the study will be conducted. Moreover the proposed approach would be low in cost and does not depend on other health system input. Potentially large numbers of people would benefit from the better understanding of simple methods of securing improved vitamin D status.

这项研究源于一项正在进行的关于老年人福尔斯和骨折的大型流行病学研究（FREE研究）。福尔斯和骨折是老年人的主要问题。这是FREEDOM（福尔斯风险流行病学：维生素D对骨骼结局的影响和其他措施）干预研究的起源。FREEDOM研究将在一项随机试验中评价公共卫生策略对减少居住在寄宿护理中的老年人（即适当的阳光照射和钙补充剂）的福尔斯和骨折的影响。本研究的主要终点是减少福尔斯和改变维生素D水平。其他终点将是运动功能、情绪、骨转换和骨折发生率的变化。我们将研究的拟议公共卫生策略，可随时转用于日常工作，并具有很好的可行性，易于推行，而且普遍适用于进行研究的院舍护理环境。此外，拟议的方法成本低，不依赖于其他卫生系统的投入。潜在的大量的人将受益于更好地了解确保改善维生素D状况的简单方法。