The Hunt for New-generation Lipopeptide Antibiotics Targeting Gram-negative ‘Superbugs’
The Hunt for New-generation Lipopeptide Antibiotics Targeting Gram-negative ‘Superbugs’
寻找针对革兰氏阴性菌“超级细菌”的新一代脂肽抗生素
批准号：
nhmrc : 1086825
负责人：
Dr Tony Velkov
金额：
$31.57万
依托单位国家：
澳大利亚
项目类别：
Career Development Fellowships
财政年份：
2015
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2015-01-01 至 2018-12-31
中文摘要
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英文摘要
The dry antibiotic discovery and development pipeline, together with the increasing incidence of bacterial resistance in the clinic has been dubbed ‘the perfect storm’. This project involves the design, synthesis and preclinical evaluation of a new generation of polymyxin-like lipopeptides that have low nephrotoxicity and specifically target polymyxin-resistant Gram-negative ‘superbugs’.
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Novel octapeptin antibiotics targeting extremely drug resistant 'superbugs'
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批准号：nhmrc : 1128891
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项目类别：Project Grants
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资助金额：$64.73万
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财政年份：2017
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负责人：Dr Tony Velkov
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依托单位：
Targeting the Achilles' heel of polymyxins: eliminating the nephrotoxicity
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批准号：nhmrc : 1085637
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项目类别：Project Grants
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资助金额：$44.9万
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财政年份：2015
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负责人：Dr Tony Velkov
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依托单位：
Polymyxin-like lipopeptide antibiotics of the future
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批准号：nhmrc : 1064896
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项目类别：Project Grants
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资助金额：$22.36万
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财政年份：2014
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负责人：Dr Tony Velkov
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依托单位：
Protecting Australia from future swine flu pandemics-Functional and Structural studies of the H1N1 swine influenza A surface glycoprotein hemagglutinin
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批准号：nhmrc : 1009876
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项目类别：Career Development Fellowships
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资助金额：$26.76万
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财政年份：2011
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负责人：Dr Tony Velkov
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依托单位：
Targeting polymyxin-resistant Gram-negative superbugs: development of novel antimicrobial lipopeptides
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批准号：nhmrc : 606573
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项目类别：NHMRC Project Grants
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资助金额：$44.08万
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财政年份：2010
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负责人：Dr Tony Velkov
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依托单位：
An examination of the role of sterol carrier protein and ileal bile acid binding protein in drug
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批准号：nhmrc : 384300
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项目类别：Early Career Fellowships
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资助金额：$18.45万
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财政年份：2006
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负责人：Dr Tony Velkov
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依托单位：
海外基金
