The interaction of LPS pathway genes with pre-natal and early exposure to LPS and allergens predicts atopy at age one

对哮喘病因的认识不足使预防策略不成功。本研究将为了解环境刺激与LPS通路基因在婴儿过敏和哮喘发生中的相互作用提供有价值的数据。由于正在调查怀孕期间的环境改变和饮食干预，拟议研究的结果将对指导过敏性疾病的预防实践具有重要意义。

The poor understanding of the cause of asthma has made prevention strategies unsuccessful. This study will provide valuable data for understanding the interactions between exposure to environmental stimuli and LPS pathway genes on the development of allergy and asthma in infants. As environmental modifications and dietary interventions during pregnancy are being investigated, the findings from the proposed study will be important in guiding prevention practices of allergic diseases.