The magic shield of the human uterus and fate of embryo implantation

点击翻译按钮获取中文摘要

Embryo implantation is a critical step in establishing pregnancy and a major hurdle in IVF treatment to overcome infertility. The uterus must remodel considerably to become “receptive” for an embryo to implant. However, how the human uterus develops this receptivity is not well understood and this knowledge gap severely hampers IVF treatment. This project will investigate a novel uterine shield controlling human uterine receptivity and its clinical application in improving IVF success rates.