Antibody-Dependent Cellular Cytotoxicity based immunity to Influenza

基于抗体依赖性细胞毒性的流感免疫

• 批准号: nhmrc : 1042634
• 负责人: Dr Ivan Stratov
• 金额: $ 45.2万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/antibody-dependent-cellular-immunity-influenza/111499
• 关键词: Antibody; Dependent; Cellular; Cytotoxicity; based

Pandemic influenza causes widespread disease, death and panic. Producing vaccines to new strains takes time. There is a need to produce vaccines that provide partial protection against unknown strains. We identified a type of anti-influenza antibody in people with prior influenza infection that may assist in reducing disease from new influenza strains. We will study these antibodies, understanding how effective they against influenza, with a view to making improved anti-influenza vaccines.

大流行性流感导致广泛的疾病、死亡和恐慌。生产针对新菌株的疫苗需要时间。需要生产对未知菌株提供部分保护的疫苗。我们在先前感染流感的人群中发现了一种抗流感抗体，这种抗体可能有助于减少新流感病毒株引起的疾病。我们将研究这些抗体，了解它们对流感的有效性，以期制造出更好的抗流感疫苗。