Towards better treatments for acral melanoma through functional genomics

通过功能基因组学更好地治疗肢端黑色素瘤

• 批准号: nhmrc : 1123217
• 负责人: Dr Nicola Waddell
• 金额: $ 98.9万
• 依托单位: Queensland Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/better-treatments-acral-functional-genomics/947107
• 关键词: Towards; better; treatments; acral; melanoma

Acral melanoma is an uncommon melanoma subtype with bad prognosis that has been poorly characterised at the molecular level. The project will conduct comprehensive analysis of acral melanoma at the DNA, RNA and protein levels. Through subsequent functional follow-up studies of key drivers of this cancer type we will identify novel drug targets to treat this disease.

肢端黑色素瘤是一种罕见的黑色素瘤亚型，预后不良，在分子水平上的特征很差。该项目将对肢端黑色素瘤进行DNA、RNA和蛋白质水平的综合分析。通过对这种癌症类型的关键驱动因素的后续功能随访研究，我们将确定新的药物靶点来治疗这种疾病。