The neuroendocrinological stress response system and stress vulnerability in youth with first-presentation borderline personality disorder

首次出现边缘性人格障碍的青少年的神经内分泌应激反应系统和应激脆弱性

• 批准号: nhmrc : 1048386
• 负责人: A/Pr Sarah Whittle
• 金额: $ 61.09万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/neuroendocrinological-stress-response-personality-disorder/112017
• 关键词: neuroendocrinological; stress; response; system; vulnerability

Borderline personality disorder (BPD) is a severe mental disorder with adverse long-term outcomes, including suicide. BPD is characterised by vulnerability to stressful life events and catastrophic responses to stress. This study of youth early in the course of BPD examines the baseline biological characteristics of the stress response system, how these characteristics might be influenced by treatment and how this relates to treatment outcome. The findings will inform early intervention for BPD.

边缘型人格障碍（BPD）是一种严重的精神障碍，具有不良的长期后果，包括自杀。BPD的特点是易受压力性生活事件的影响和对压力的灾难性反应。这项研究的青年早期的过程中BPD检查基线的压力反应系统的生物学特征，这些特征如何可能受到影响的治疗，以及如何这与治疗结果。这些发现将为BPD的早期干预提供信息。