The pharmacology of sulfotransferase 4A1
The pharmacology of sulfotransferase 4A1
批准号:
nhmrc : GNT1099135
负责人:
Dr Neville Butcher
金额:
$57.7万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
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英文摘要
SULT4A1 is not a sulfotransferase, but a sulfotransferase inhibitor. It forms high affinity heterodimers with other sulfotransferases via a conserved dimerisation site in its carboxyl terminus attenuating catalytic activity. Consequently, it is important for the metabolism of numerous important molecules including estrogens, thyroid hormones, neurotransmitters and many therapeutic agents.
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The pharmacology of sulfotransferase 4A1
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批准号:nhmrc : 1099135
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项目类别:Project Grants
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资助金额:$39.56万
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财政年份:2016
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负责人:Dr Neville Butcher
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依托单位:
Role of sirtuins in the regulation of the carcinogen metabolising arylamine N-acetyltransferases
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批准号:nhmrc : 1083036
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项目类别:Project Grants
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资助金额:$21.83万
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财政年份:2015
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负责人:Dr Neville Butcher
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依托单位:
Role of the drug metabolising enzyme arylamine N-acetyltransferase 1 in breast cancer
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批准号:nhmrc : 1024769
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项目类别:Project Grants
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资助金额:$40.02万
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财政年份:2012
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负责人:Dr Neville Butcher
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依托单位:
Pharmacological Targeting of Arylamine N-Acetyltransferase I
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批准号:nhmrc : 569695
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项目类别:NHMRC Project Grants
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资助金额:$31.65万
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财政年份:2009
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负责人:Dr Neville Butcher
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依托单位:
海外基金