Australian Genomewide Association Study in Osteoporosis

澳大利亚全基因组协会骨质疏松症研究

• 批准号: nhmrc : 511132
• 负责人: Prof David Evans
• 金额: $ 58.86万
• 依托单位: Garvan Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/australian-genomewide-association-study-osteoporosis/96862
• 关键词: Australian; Genomewide; Association; Study; Osteoporosis

Osteoporosis is a common condition in which bone strength is reduced due to reduced amount and quality of bone. Reduced bone strength means an increased risk of fracture. Osteoporotic fractures occur in 1 in 2 women and 1 in 3 men in their lifetime, and the likelihood of suffering osteoporotic fracture increases with age. Most of the risk of developing osteoporosis is genetic, but few of the genes involved have been identified. Our goal is to identify those genes.

骨质疏松症是一种常见的病症，其中由于骨的数量和质量降低而导致骨强度降低。骨强度降低意味着骨折风险增加。骨质疏松性骨折发生在1/2的妇女和1/3的男子在他们的一生中，并遭受骨质疏松性骨折的可能性随着年龄的增长而增加。大多数骨质疏松症的风险是遗传的，但很少有相关的基因被确定。我们的目标是找出这些基因。