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Major Histocompatibility Complex (MHC) Genetics of Ankylosing Spondylitis

Major Histocompatibility Complex (MHC) Genetics of Ankylosing Spondylitis
强直性脊柱炎的主要组织相容性复合体 (MHC) 遗传学
批准号：
nhmrc : 569829
负责人：
Prof David Evans
金额：
$37.92万
依托单位：
The University of Queensland
依托单位国家：
澳大利亚
项目类别：
NHMRC Project Grants
财政年份：
2009
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2009-01-01 至 2011-12-31
来源：
https://researchdata.edu.au/major-histocompatibility-complex-ankylosing-spondylitis/99248
关键词：
MajorHistocompatibilityComplexMHCGenetics

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中文摘要
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英文摘要
Ankylosing spondylitis (AS) is the prototypic condition of a group of types of inflammatory arthritis called 'seronegative spondyloarthropathies'. These conditions are the most common form of inflammatory arthritis in white populations and occur worldwide. One third of the risk of developing AS is determined by genes within a region called the 'major histocompatibility complex' (MHC), in addition to the gene HLA-B27, the main gene causing AS. We aim to identify the remaining MHC genes.
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Developing and applying statistical genetics methods to identify genes, molecular biomarkers and environmental agents that causally affect risk of complex musculoskeletal diseases
  • 批准号：
    nhmrc : GNT1137714
  • 项目类别：
    Research Fellowships
  • 资助金额：
    $70.74万
  • 财政年份：
    2018
  • 负责人：
    Prof David Evans
  • 依托单位：
Developing and applying statistical genetics methods to identify genes, molecular biomarkers and environmental agents that causally affect risk of complex musculoskeletal diseases
  • 批准号：
    nhmrc : 1137714
  • 项目类别：
    Research Fellowships
  • 资助金额：
    $47.83万
  • 财政年份：
    2018
  • 负责人：
    Prof David Evans
  • 依托单位：
    The University of Queensland
Development and application of a Mendelian randomization framework aimed at dissecting the biological basis of ankylosing spondylitis and other complex diseases
  • 批准号：
    nhmrc : GNT1125200
  • 项目类别：
    Project Grants
  • 资助金额：
    $27.97万
  • 财政年份：
    2017
  • 负责人：
    Prof David Evans
  • 依托单位：
Development and application of a Mendelian randomization framework aimed at dissecting the biological basis of ankylosing spondylitis and other complex diseases
  • 批准号：
    nhmrc : 1125200
  • 项目类别：
    Project Grants
  • 资助金额：
    $19.3万
  • 财政年份：
    2017
  • 负责人：
    Prof David Evans
  • 依托单位：
    The University of Queensland
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