Benefit of 2D-strain surveillance in improving cardiovascular outcomes in cancer patients undergoing cardiotoxic chemotherapy

二维应变监测对改善接受心脏毒性化疗的癌症患者心血管结局的益处

• 批准号: nhmrc : 1119955
• 负责人: A/Pr Andre La Gerche
• 金额: $ 163.76万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/benefit-2d-strain-cardiotoxic-chemotherapy/946399
• 关键词: Benefit; 2D; strain; surveillance; improving

Cancer survivors are susceptible to heart failure (HF) caused by heart muscle damage from chemotherapy. The current testing for this problem is based on a measure that cannot identify minor changes of cardiac function. Cardiac strain is a sensitive new marker of cardiac function which is predictive of overt dysfunction & HF. This study seeks to identify whether strain can be used to assign treatments that lead to improved cardiac function and are eventually associated with a reduction in HF.

癌症幸存者易受性疗法造成心肌损害引起的心力衰竭（HF）。当前对此问题的测试基于无法识别心脏功能的较小变化的度量。心脏应变是心脏功能的敏感新标记，可预测明显的功能障碍和HF。这项研究试图确定是否可以使用菌株来分配导致心脏功能改善的治疗方法，并最终与HF减少有关。