Benefit of 2D-strain surveillance in improving cardiovascular outcomes in cancer patients undergoing cardiotoxic chemotherapy

二维应变监测对改善接受心脏毒性化疗的癌症患者心血管结局的益处

• 批准号: nhmrc : 1119955
• 负责人: A/Pr Andre La Gerche
• 金额: $ 163.76万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/benefit-2d-strain-cardiotoxic-chemotherapy/946399
• 关键词: Benefit; 2D; strain; surveillance; improving

Cancer survivors are susceptible to heart failure (HF) caused by heart muscle damage from chemotherapy. The current testing for this problem is based on a measure that cannot identify minor changes of cardiac function. Cardiac strain is a sensitive new marker of cardiac function which is predictive of overt dysfunction & HF. This study seeks to identify whether strain can be used to assign treatments that lead to improved cardiac function and are eventually associated with a reduction in HF.

癌症幸存者容易患上由化疗引起的心肌损伤引起的心力衰竭(HF)。目前对这一问题的测试是基于一种无法识别心功能微小变化的测量方法。心脏劳损是一种敏感的新的心功能标志物，可以预测明显的心功能障碍&心力衰竭。这项研究试图确定菌株是否可以用于分配能够改善心功能并最终与减少心力衰竭相关的治疗。