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Biological function of the chemokine receptor 6 expression on B cells

Biological function of the chemokine receptor 6 expression on B cells
B 细胞上趋化因子受体 6 表达的生物学功能
批准号:
nhmrc : 329210
负责人:
Prof Heinrich Korner
金额:
$16.1万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2005
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2005-01-01 至 2007-12-31

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中文摘要
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英文摘要
The correct movement of cells is important for the defence of the body against micro-organisms. White blood cells have to arrive quickly at the site of an infection and information about this infection has to be spread. White blood cells that navigate the body are using molecules on their surface termed as receptors which help them to detect the scent of their target. One of these receptors is located on white blood cells that produce antibodies and enables these cells to migrate to appropriate tissues . We want to know more about the biological role of this receptor and its functions during the immune response to pathogens. It would be of significant importance to understand the impact of these cell surface receptors in detail because this could open the possibility to new therapies of infectious diseases and chronic inflammation.
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Absence of CC chemokine receptor 6 dysregulates the humoral immune response.
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  • 批准号:
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