Cardiac matrix modulation by Platelet Derived Growth Factor to improve outcomes after myocardial infarction

通过血小板衍生生长因子调节心脏基质以改善心肌梗死后的预后

• 批准号: nhmrc : 2002783
• 金额: $ 9.6万
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cardiac-matrix-modulation-myocardial-infarction/1780455
• 关键词: Cardiac; matrix; modulation; Platelet; Derived

This project is directed towards improving the poor outcome in patients suffering heart failure. Whilst rates of some cardiovascular diseases are decreasing, heart failure incidence is rising significantly. Once end stage heart failure occurs, heart transplantation is possible but has several limitations including organ availability. This research into cardiac regeneration could potentially lead to a significant therapy for heart failure, thereby translating into life-saving outcomes.

该项目旨在改善心力衰竭患者的不良预后。虽然一些心血管疾病的发病率正在下降，但心力衰竭的发病率正在显著上升。一旦发生终末期心力衰竭，心脏移植是可能的，但有一些限制，包括器官的可用性。这项关于心脏再生的研究可能会导致心力衰竭的重大治疗，从而转化为挽救生命的结果。