Cells and Nanobiomaterials to Treat and Prevent Pelvic Organ Prolapse

治疗和预防盆腔器官脱垂的细胞和纳米生物材料

• 批准号: nhmrc : GNT1159677
• 金额: $ 139.73万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cells-nanobiomaterials-treat-organ-prolapse/1379086
• 关键词: Cells; Nanobiomaterials; Treat; Prevent; Pelvic

Pelvic organ prolapse is a hidden, debilitating gynaecological disorder affecting 25% of women causing sexual, bladder and bowel dysfunction. Prolapse is the herniation of the uterus, bladder, or bowel into the vagina as a result of childbirth injury. Surgical treatment often fails and the use of vaginal mesh has been banned due to unacceptable side effects. We are developing a cell-based therapy using a woman’s own endometrial stem cells to repair the damaged tissue.

盆腔器官脱垂是一种隐藏的，使人衰弱的妇科疾病，影响25%的妇女，造成性，膀胱和肠道功能障碍。脱垂是由于分娩损伤导致的子宫、膀胱或肠疝入阴道。手术治疗经常失败，由于不可接受的副作用，阴道网片的使用已被禁止。我们正在开发一种基于细胞的疗法，使用女性自己的子宫内膜干细胞来修复受损组织。