Characterising the role of IL-37 in the development of H. pylori infection.

H.幽门螺杆菌感染超过50%的世界人口，并且是胃癌的病原体，胃癌是世界范围内与癌症相关的死亡的第二大原因。螺杆菌感染幽门螺杆菌发生在儿童早期，并在宿主体内终生存在，导致免疫抑制，从而阻止从个体清除感染。我们将研究一个新发现的机制H。pylori诱导的人体免疫抑制，试图提供新的治疗方法。

H. pylori infects more than 50% of the worlds population and is the causative agent of gastric cancer, the second leading cause of cancer-related deaths worldwide. Infection with H. pylori occurs during early childhood and persists within the host for life, causing immune suppression and therefore preventing clearance of the infection from the individual. We will examine a newly identified mechanism of H. pylori-induced immune suppression in humans in an attempt to provide novel treatments.