CHARACTERIZATION OF A NEW SUBTYPE OF AGGRESSIVE BREAST CANCER

侵袭性乳腺癌新亚型的特征

• 批准号: nhmrc : GNT1130212
• 负责人: A/Pr Andrew Redfern
• 金额: $ 76.32万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterization-new-subtype-breast-cancer/1347797
• 关键词: CHARACTERIZATION; NEW; SUBTYPE; AGGRESSIVE; BREAST

Much effort has been invested in the sequencing of cancer genomes, leading to the identification of genes linked to aggressive subtypes. There is now a need to confirm the importance of these genes and to exploit these findings for patient therapies. We have identified a new cancer driver controlling an aggressive type of breast tumour which may act through one carbon/folate metabolism. We aim to map the inner workings of these cancers to devise effective targeted drugs for these patients.

在癌症基因组测序方面已经投入了大量的努力，从而鉴定出与侵袭性亚型相关的基因。现在需要确认这些基因的重要性，并利用这些发现进行患者治疗。我们已经确定了一种新的癌症驱动因素，它控制着一种侵袭性的乳腺肿瘤，可能通过一种碳/叶酸代谢起作用。我们的目标是绘制这些癌症的内部工作原理，为这些患者设计有效的靶向药物。