Characterization of Sex-Specific Differences in Cardiovascular Adaptation in the First Three Years of Life

生命前三年心血管适应的性别差异特征

• 批准号: nhmrc : 569285
• 负责人: Prof Ian Wright
• 金额: $ 37.86万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterization-sex-specific-years-life/94553
• 关键词: Characterization; Sex; Specific; Differences; Cardiovascular

Male babies born significantly premature are up to twice likely to die than females. The reasons for this are unknown. This study will determine the cardiovascular differences in male and female babies born preterm and will examine how they adapt over the first 5 days. Defining the mechanisms that contribute to the difference in mortality between the sexes will also show how changes starting around birth affect the way the blood pressure system functions for life, a major lifetime stroke risk.

早产男婴死亡的可能性是女婴的两倍。原因不明。这项研究将确定早产男婴和女婴的心血管差异，并将研究他们如何在前5天适应。定义导致性别之间死亡率差异的机制也将显示出生前后开始的变化如何影响血压系统终身功能的方式，这是一生中主要的中风风险。