the molecular basis for the initiation of squamous differentiation and how it is disrupted in oral cancers

鳞状分化起始的分子基础及其在口腔癌中如何被破坏

• 批准号: nhmrc : 511250
• 负责人: Orla Gannon
• 金额: $ 4.31万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Postgraduate Scholarships
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-basis-initiation-oral-cancers/115591
• 关键词: molecular; basis; initiation; squamous; differentiation

Squamous cancers of the mouth, nose and throat occur due to defects in the cells that line these regions. We have shown that a major defect is that the lining cells are unable to stop growing and mature into cells that provide a barrier against the enviro

口腔、鼻子和喉咙的鳞状细胞癌是由于这些区域的细胞缺陷而发生的。我们已经证明，一个主要缺陷是衬里细胞无法停止生长并成熟为针对周围环境提供屏障的细胞