Regulation of ribosomal RNA gene chromatin during malignant transformation.
Regulation of ribosomal RNA gene chromatin during malignant transformation.
批准号:
nhmrc : GNT1100654
负责人:
Dr Elaine Sanij
金额:
$88.25万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The overarching goal of this proposal is to determine the molecular basis for tumour cell dependence on activated ribosomal RNA gene repeats (rDNA). Our working model posits that rDNA repeats become activated through changes in rDNA chromatin structure that include increased binding of the RNA Polymerase I transcription factor UBF.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Regulation of ribosomal RNA gene chromatin during malignant transformation.
-
批准号:nhmrc : 1100654
-
项目类别:Project Grants
-
资助金额:$60.65万
-
财政年份:2016
-
负责人:Dr Elaine Sanij
-
依托单位:
Genomic analysis of DNA binding and gene regulation by the chromatin remodelling factor UBF
-
批准号:nhmrc : 1043143
-
项目类别:Project Grants
-
资助金额:$41.63万
-
财政年份:2013
-
负责人:Dr Elaine Sanij
-
依托单位:
海外基金